- 作者: Vladimir R Kaberdin; Dharam Singh; Sue Lin-Chao
- 作者服務機構: Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan, R.O.C.
- 中文摘要: --
- 英文摘要:
RNA synthesis and decay counteract each other and therefore inversely regulate gene
expression in pro- and eukaryotic cells by controlling the steady-state level of
individual transcripts. Genetic and biochemical data together with recent in depth
annotation of bacterial genomes indicate that many components of the bacterial RNA
decay machinery are evolutionarily conserved and that their functional analogues
exist in organisms belonging to all kingdoms of life. Here we briefly review
biological functions of essential enzymes, their evolutionary conversation and
multienzyme complexes that are involved in mRNA decay in Escherichia coli and
discuss their conservation in evolutionarily distant bacteria. - 中文關鍵字: --
- 英文關鍵字: --