• 作者： 呂維明；陳炳亨；倪瓏文
• 作者服務機構： 國立臺灣大學化學工程學系
• 中文摘要： 本文利用數目平衡模式解析攪拌反應槽之攪拌現象，並利用模式之參數?規模放大之基準。
  本研究結果顯示此基準之應用，導致單一之效應甚便於放大之設計。本文亦利用Kono等人之醱酵動力學模式解析所得 數據，其結果顯示麩酸醱酵中麩酸之生?只與非繁殖菌濃度有關。
  本?究結果曾被利用於修改工廠?有之大型醱酵槽及設計更大之醱酵槽而獲得頗佳之效果。
• 英文摘要： The effect of power consumption and mixing intensity of glutamic acid fermentation in a semi-batch operation is studied in both 5001 pilot scale fermenter and commercial scale fermenters. A population balance model is used to describe the mixing of fluid in the system and a parameter of the model is defined as the mixing intensity which can be seen as an index of homogeneity of the system.
  A unique relationship between yield and mixing intensity was obtained to solve the problem in the multiple relationship of power consumption per unit volume and yield due to different structure in fermenter design.
  The data obtained from batch operations were also analyzed by using, a kinetic model proposed by Kono and Asai. The results show that the yield of glutamic acid associates only with the concentration of nongrowth cell and is not affected by the concentration of the growth cells.
  The result obtained in this study was applied to modify the design of an existing 100 kl fermenters, and design a new 160 kl fermenter. The modification in design has resulted in an improvement of more than 15% yield in the 100 kl fermenters and also demonstrated excellent performance in the new 160 kl fermenter as well as in the 100 kl fermenters.
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