- 作者: 沈旭 ; 單軍 ; 孫紅保 ; 康北笙
- 作者服務機構: Department of Chemistry, Tongji University, Shanghai 200092, China
- 中文摘要: One new Mn(II) complex, 1, MnL/sub 2/(phen)/sub 2/(L=p-nitrophenylcyanamido-N, phen=.omicron.-phenanthroline) has been synthesized and crystallographically characterized. Complex 1 was obtained from the desulfurization and hydrolysis of H/sub 2/pmt(H /sub 2/pmt=N-(p-nitrophenyl)-N'-(methoxycarbonyl)thiourea) in alkaline media. 1 crystallized in the triclinic space group p-1 with a = 11.0320 (3), b = 11.7831(4), c = 12.9288(4).ANG.; .alpha.= 87.3590(10), .beta.= 81.7500(10), .gamma.= 84.0080(10). degree.. Preliminary pharmacological tests showed that complex 1 exhibited definite inhibition activities against human ovary tumor 3A0 and mice P388 in vitro.
- 英文摘要: --
- 中文關鍵字: Manganese (Ii) Complex; Synthesis; Crystal Structure; Antitumor Activity; Thiourea
- 英文關鍵字: 二價錳錯合物;合成;晶體結構;抗腫瘤作用;硫化尿素