- 作者: Anne Robert, Odile Dechy-Cabaret, Jerome Cazelles, Francoise Benoit-Vical and Bernard Meunier*
- 作者服務機構: Laboratoire de Chimie de Coordination du CNRS, 205 route de Narbonne, 31077 Toulouse cedex 4, France
- 中文摘要: A short review of the currently used antimalarial drugs is reported. The molecular aspects of the different possible mechanisms of action of artemisinin is documented, including recent data on heme alkylation. The preparation and the in vitro antimalarial activity of new modular molecules named “trioxaquines” is also presented.
- 英文摘要: --
- 中文關鍵字: Artemisinin; Malaria; Peroxide; Quinoline; Trioxaquine.
- 英文關鍵字: Artemisinin; Malaria; Peroxide; Quinoline; Trioxaquine.