• 作者： Mitchell L. Borke; Bongja K. Lee; 李宗基
• 作者服務機構： 美國賓夕法尼亞州都肯大學
• 中文摘要： CN (5x10 M）和CH CSNH (5x10 M)增加血青素的P 值，分別為 100% 及 110% 。CN 與血青素在室溫下形成 1:1 複合物 : K = 2.3 Mw M（Mw為血青素的分子量）。此反應較強，並可解釋CN 對血青素吸氧能力的減弱。Mn(II)和F 對血青素吸氧的能力雖無甚影響，可是 NMR 的測量顯示Mn(II)和血青素的活化部位確有作用。
• 英文摘要： eyanide（5xl0 M）and thioacetamide（5x10 M）increase the P vdues（Po required for 50%oxygenation）of hemocyanin by 100% and 110%, respectively. Using an ion-exchange method involving CN , we have found that cyanide forms a 1:1 complex with hemocyanin in the concentration rangeexamined: k =2.3 x Mw M at room temperature, where K is association constant and Mw is molecularweight of hemocyanin. This strong binding of cyanide to hemocyanin is to be expected from the effectof this ion on the oxygenation of hemocyanin. The effects of manganese(II) ion and fluoride on the oxygenation of hemocyanin are found to be weak. The nmr measurements, however, suggest that man-ganese(II) ion does have some interactions with the active site of hemocyanin.
• 中文關鍵字： Mn(Ⅱ) and fluoride interactions with hemocyanin; small ligan interactions with hemo-cyanin; Busycon canaliculatum hemocyanin; oxygenation of hemocyanin
• 英文關鍵字： --