- 作者: H. A. A. Medien
- 作者服務機構: Department of Chemistry, Faculty of Science, Ain Shams University, Cairo, Egypt
- 中文摘要: Kinetic studies were performed to investigate the mechanism of Schiff base formation in the reaction between aromatic aldehydes and 1,5-diamino-4,8-dihydroxypyridazino[4,5-d]pyridazine (DDPP). The studies were conducted at different temperatures with ethanol as solvent and acetic acid as catalyst. It is proposed that the first step involves the reaction of the aldehyde with a solvated proton (I.e. specific acid catalysis). Depending on the acidity of the medium, free or mono-protonated (DDPP) attacks the carbonyl group to form a carbinol-amine intermediate which then dehydrates to form the product. Plot of DH# versus DS# for the reaction gave a good straight line with isokinetic temperature of 343.15 K. Good linear relationship was obtained from the plot of log k against s° values. The rate law derived from the proposed mechanism is in agreement with the experimental data and observations. The effects of meta and para substituents of benzaldehyde toward reactivity have been studied.
- 英文摘要: --
- 中文關鍵字: Aromatic aldehydes; Kinetic.
- 英文關鍵字: Aromatic aldehydes; Kinetic.