• 作者： 張瑞烽; 許芬芳; 彭健芳; 葉丙炎
• 作者服務機構： 高雄醫學院; 微生物學科; 實驗診斷
• 中文摘要： 自民國70年9月至71年9月問，自病童分離出244株的沙門氏桿菌。在所分離的菌株血清型中，以S. tyhpimurium與S. muenchen最為常見。其中238株（97.5%）帶有一種或多種的抗藥性，尤以對ampicillin, chloramphenicol, kanamycin, streptomycin, tetracycline, trimethoprim-sulfamethoxazole抗藥性最為常見。抗藥性轉移實驗的絨果顯示，有80%（195/244）的菌株，可將一種或多種藥物的抗藥性，轉移給不帶質因子的大腸桿菌。這些藥物分別為ampicillin, chloramphenicol, kanamycin, streptomycin, tetracycline, gentamicin, trimethoprim-sulfamethoxazole。在受試的沙門氏桿菌中，尚無可將 nalidixic acid 與colistin抗藥性轉移的菌株出現。
• 英文摘要： A total of 244 salmonella strains isolatedfrom children with diarrhea were collectedbetween Sept. 1981 and Sept. 1982. Salmonellatyphimurium and Salmo nella muenchen werethe most common serotypes. About 98% (238/244) of the isolates showed resistance to oneor more antimicrobial agents. Resistance toampicillin, chloramphenicol, kanamycin, streptomycin, tetracycline, and trimethoprirm-sulfamethoxazole were often observed. Tran-sferable drug resistance were demonstrated in195 strains. Resistance to ampicillin, chloram-phenicol, kanamycin, streptomycin, tetracy-cline, gentamicin, trimethoprim, sulfametho-xazole, could be transferred en block orpartially to plasmidless Eecherichia coli. Incontrast, transfer resistance to nalidixic acidand colistin were not encountered.
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