- 作者: 李存魁, 馬玉潔, 曹玲華
- 作者服務機構: College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046, P. R. China
- 中文摘要: A series of novel pyrazolyl-substituted 1,3,4-oxadiazole derivatives (4a-4o) were prepared by cyclization of the intermediate N¢-((3-aryl-l-phenyl-pyrazol-4-yl)methylene)arylhydrazide with acetic anhydride. The structures of the new compounds were confirmed by IR, 1H NMR, MS and elemental analysis. Furthermore, preliminary bioassay of some of the title compounds indicated that they exhibited moderate inhibition against HIV-1 PR.
- 英文摘要: --
- 中文關鍵字: 4-Formylpyrazole; 1,3,4-Oxadiazole; Biological activity.
- 英文關鍵字: --