- 作者: --
- 作者服務機構: Chemistry Department, Faculty of Science, Benha University, Benha - Egypt
- 中文摘要: b-(4-Chlorobenzoyl)acrylic acid (1) proved to be a convenient precursor for the synthesis of a variety of heterocyclic systems through the reaction with compounds containing active methylene groups under Michael reaction conditions. Also, the reactivity of Michael adduct towards nitrogen nucleophiles was investigated to afford diazepine, indazole, isoxazole and quinazoline derivatives. Some of the synthesized compounds were screened for their biological activity.
- 英文摘要: --
- 中文關鍵字: Indazole; Isoxazole; Michael adduct; Diazepine and quinazoline derivatives.
- 英文關鍵字: --