• 作者： 張丙龍
• 作者服務機構： 國立臺灣大學醫學院解剖學科
• 中文摘要： 注射有 5mg 過氧化氫?之10 生理食?水到大白鼠的前眼房內直向虹膜7小時後在有交感神經分佈於此區域的
  神經節細胞之細胞質內可看到很多過氧化氫?反應的顆粒。以光學顯微鏡觀察時過氧化氫?呈現濃褐色的顆粒。如以電
  子顯微鏡觀察時此顆粒呈現在神經節細胞的平滑內質網之小囊及小管內以及溶?體內。此過氧化氫?亦存在於神經節內
  的軸突裹面之平滑內質網的小囊及小管內。有過氧化氫?反應的神經細胞分散於神經節內，輸送過氧化氫?的速度為每
  小時 4mm 。本研究結果顯示注射過氧化氫? 2 天後的大白鼠，其交感神經細胞呈現最強的過氧化氫?反應並且其樹狀
  突亦有輸送過氧化氫?的能力。注射過氧化氫?7天後此過氧化氫?從神經細胞消失，此可能因為被細胞內的溶?體所
  消耗的結果。
  準
• 英文摘要： Seven hours after injection of 5 mg of horseradish peroxidase (HRP) dissolved in 10 1 normal salineinto the anterior chamber of the eye directly into the iris of rats, sympathetic ganglion cells projecting tothese regions were detected by numerous HRP-positive granules in their cytoplasm. By light microscopy,these HRP-labelled granules appeared as heavy brown granules, ultrastructurally they were demonstratedin the vesicles and tubules of smooth endoplasmic reticulum and in the lysosome-like dense bodies in theperikaryon of the neuron. The HRP reaction product was also detected in the vesicles and tubules ofsmooth endoplasmic reticulum within the axons in the superior cervical ganglion．The neurons projectingto the iris dilator muscles, which showed an HRP-positive reaction were scattered in the ganglion, and therate of retrograde axonal transport of HRP was 4mm/hour. The present study revealed that the greatestamount of strong reaction product was found in the neurons from animals 2 days after injection of HRP,and that HRP-labelled ganglion cells also have the capacity for dendritic transport of HRP. The HRP reac-tion product that disappeared from ganglion cells by 7 days post-injection of HRP was probably due tothe lysosomal degradation.
• 中文關鍵字： rat; horseradish peroxidase; sympathetic neurons; smooth endoplasmic reticulum; lyso-some-like dense bodies
• 英文關鍵字： --