- 作者: 邱念華 ; 徐鳳麟 ; 闕甫 等
- 作者服務機構: 華夏工商專校化學工程科
- 中文摘要: The antihypertensive activity of dl- tetrahydropalmatine hydrochloride (THP), isolated from the tubers of Corydalis racemosa (Thunb.) Pers. (Papaveraceae), was investigated in spontaneously hypertensive rats (SHRs) using intravenous injection. A dose -dependent lowering of blood pressure was observed in SHRs. Decrease of plasma noradrenaline was also obtained in SHRs that received injection of THP. Direct injection of THP into brain lowered the blood pressure and plasma noradrenaline. This antihypertensive action of THP appears to be produced mainly by an effect on central nervous system to lower sympathetic tone in SHRs.
- 英文摘要: --
- 中文關鍵字: Antihypertensive Activity; Alkaloid; Corydalis Racemosa
- 英文關鍵字: 抗高血壓活性;生物鹼