• 作者： 張丙龍
• 作者服務機構： 國立台灣大學醫學院解剖學科
• 中文摘要： 定量結果顯示倉鼠松果腺內之乙醯膽鹼?為7.05 摩爾。頸上神經節摘除兩星期後約消失了22％的乙醯膽鹼?。以
  電子顯微鏡觀察後發現此酵素是存在於正常松果腺細胞之核周池，高爾基氏器及平滑內質網內。此酵素亦存在於松果腺
  內之無髓鞘腎上腺素激導性神經及其末端以及在有髓鞘神經內。摘除頸上神經節後松果腺內之腎上腺素激導性神經及其
  末端完全消失，但一些松果腺細胞內尚存在著一些乙醯膽鹼?顯示此等細胞能產生此乙醯瞻膽鹼?。由本論文發現及參考
  過去之論文結果也許可作如下之推論：倉鼠松果腺內之無髓鞘腎上腺素激導性神經是來自頸上神經節，此神經能將新腎
  上腺素及乙醯膽鹼從頸上神經節輸送到松果腺內來，在腺內此乙醯膽鹼可能會引起松果腺細胞產生乙醯膽鹼?。
  增
• 英文摘要： Biochemical assay reveals that acetylcholinesterase activity in the pineal glands of normal adulthamsters is 7.05 M. Two weeks after superior cervical ganglionectomy, about 22% of acetylcholinesteraseis lost. Ultrastructurally, acetylcholinesterase activity is localized in the perinulear space, Golgi complex，and smooth-surfaced endoplasmic reticulum of the pinealocytes. Enzyme reaction product is also detectedin the unmyelinated adrenergic nerve fibers and their endings, as well as in the myelinated nerve fiberswithin the pineal gland. After superior cervical ganglionectomy, the unmyelinated adrenergic nerve fibersand their endings completely disappears, while some acetylcholinesterase activity still remains in the pinea-locytes, suggesting that these cells are able to produce acetylcholinesterase. On the basis of the presentfindings, together with previous data, it is suggested that unmyelinated adrenergic nerve fibers in thehamster pineal gland are derived from the superior cervical ganglion, and that they convey noradrenalineand some acetylcholine to the pineal gland. In all likelihood, it is acetylcholine that induces pinealocytesto produce acetylcholinesterase.
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