- 作者: Harold J Ting; Fadi T Khasawneh
- 作者服務機構: Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California, USA
- 中文摘要: --
- 英文摘要:
While there have been many reports investigating the biological activity and signaling mechanisms of isoprostanes,
their role in biology, particularly in platelets, appears to still be underestimated. Moreover, whether these lipids have
their own receptors is still debated, despite multiple reports that discrete receptors for isporpstanes do exist on
platelets, vascular tissues, amongst others. This paper provides a review of the important literature of isoprostanes and
provides reasoning that isoprostanes should be classified as orphan ligands until their receptor(s) is/are identified. - 中文關鍵字: --
- 英文關鍵字: --