- 作者: Amod Sharma
- 作者服務機構: Department of Physiology, Siriraj Hospital, Mahidol University, Bangkok, Thailand
- 中文摘要: --
- 英文摘要: Animal studies suggest that chronic monosodium glutamate (MSG) intake induces kidney damage by oxidative stress. However, the underlying mechanisms are still unclear, despite the growing evidence and consensus that α-ketoglutarate dehydrogenase, glutamate receptors and cystine-glutamate antiporter play an important role in up-regulation of oxidative stress in MSG-induced renal toxicity. This review summaries evidence from studies into MSG-induced renal oxidative damage, possible mechanisms and their importance from a toxicological viewpoint.
- 中文關鍵字: --
- 英文關鍵字: Monosodium glutamate; Kidney; Oxidative stress; Glutamate receptors; α-Ketoglutarate dehydrogenase