- 作者: 戴政
- 作者服務機構: 中央研究院統計研究所籌備處
- 中文摘要: 本文旨在探討當一數量遺傳性疾病與一標識基因座間存有相關聯時之連鎖互換率估算方法。首先,作者提出一“最小平方誤差”觀念,以進行該疾病之主效基因分派,然後利用此結果與所提出之方法去估算當疾病與標識基因座間有關聯時之連鎖分析。
- 英文摘要: This paper proposes a method to deal with linkage analysis under the existence of association be-tween a disease and a marker locus. We specially consider the disease as a quantitative trait. At first, wepropose a so-called "a minimum sum of square errors approach" to classify individuals in a family genetical-ly, then use the classification results to detect linkage with association by the developed method.
- 中文關鍵字: estradiol; progesterone; luteinizing hormone
- 英文關鍵字: --