- 作者: Kuo-Hsiung Lee
- 作者服務機構: Natural Products Laboratory, Division of Medicinal chemistry and Natural Products, School of Pharmacy, University of North carolina, Chapel Hill, N.C., USA
- 中文摘要: --
- 英文摘要: This review article focuses on recent research in my lab-oratory on various classes of compounds that possesspotent antitumor activity. These compounds were ob-tained by bioactivity- and mechanism of action-directedisolation and characterization coupled with rational drugdesign-based modification and analog synthesis. Struc-tural modification, structure-activity relationship, andmechanism of action studies will be discussed.
- 中文關鍵字: --
- 英文關鍵字: Anticancer agents. Drug design. Natural products. Synthetic analogs