• 作者： Ahmad S. Shawali*, Magda A. Abdallah and Mohie E. M. Zayed
• 作者服務機構： Department of Chemistry, Faculty of Science, University of Cairo, Giza, Egypt
• 中文摘要： Bis-hydrazonoyl chloride 1 reacts regioselectively with 3-mercapto-1,2,4-triazole 2a, 2,3-dihydro-3-thioxo-1,2,4-triazin-5(4H)-one 2b and 2-mercaptobenzimidazole 2c to give the hitherto unknown annelated 2,3-bis-(phenylhydrazono)thiazoles 6a-c, respectively. Reactions of 1 with the methylthio derivatives of such heterocycles afforded the annelated 3,3￠-bis-(1,2,4-triazoles) 11a-c, respectively. Similar reaction of 1 with 2-phenylamino-4(3H)-pyrimidinones 4 gave 2,3-bis(phenylhydrazono)imidazo[1,2-a]pyrimidin-5(1H)-ones 16. Oxidation of 6c yielded the corresponding bis(phenylazo) derivative 15. The regiochemistry of the studied reactions is discussed.
• 英文摘要： --
• 中文關鍵字： Hydrazones; Synthetic methods; Thiazoles
• 英文關鍵字： Hydrazones; Synthetic methods; Thiazoles