- 作者: Aamer Saeed
- 作者服務機構: Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan
- 中文摘要: A two step synthesis of title isocoumarin isolated from Homalium longifolium and its conversion into corresponding 3,4-dihydroisocoumarin has been described. 3,4-Dimethoxybenzoyl chloride on condensation with homophthalic acid afforded 3-(3¢,4¢-dimethoxyphenyl)isocoumarin which was demethylated to furnish the 8-desoxythunberginol A, whereas its sequential saponification, reduction and demethylation yielded the (±)-8-desoxy-3,4-dihydrothunberginol A. The synthesized compounds were examined in vitro for antibacterial activity.
- 英文摘要: --
- 中文關鍵字: Homalium longifolium; Hydrangea macrophylla; Thunberginol A; Isocoumarins; Antibacterial.
- 英文關鍵字: Homalium longifolium; Hydrangea macrophylla; Thunberginol A; Isocoumarins; Antibacterial.