• 作者： 陳淑姿; 蔡明世; 沈清良
• 作者服務機構： 國立成功大學醫學院解剖科; 省立臺南醫院神經外科
• 中文摘要： 本實驗是以免疫組織化學法來研究神經加壓素在臺灣獮猴中樞神經系統的分佈。結果發現含神經加壓素的神經元廣泛地分佈於前腦中，主要的區域包括邊緣系統、基底核和大腦皮質；特別是杏仁核、膈區、新線條體、帶狀核和腦島等部位；另外終末線條核和視前區也有顯著的反應。本實驗也發現從大腦皮質到脊髓含大量神經加壓素的纖維，例如正中隆起、海馬回、丘腦下部弓狀核、中心灰質及脊髓背角等。本文詳細討論臺灣獮猴的神經加壓素分佈，並與大白鼠、日本猴及人類比較。另外也稍略提及神經加壓的可能功能。
• 英文摘要： The distribution of neurotensin-like immunoreactivity was investigated in the central nervous systemof the Formosan monkey employing immunohistochemical techniques. Neurotensin-containing cells werefound to be widely distributed in the forebrain. The principal densities of neurotensin-like neuronal per-ikarya were located in the limbic system, the basal ganglion and the cerebral cortex; particularly in theamygdala, the septum, the neostriatum, the claustrum and the insula. The stria terminalis and the preopticarea were also rich in immunostained neurotensin-like neurons. A large number of immunoreactive fiberswere observed from the cerebral cortex to the spinal cord in locations such as the median eminence, thearcuate nucleus, the hippocampus, the central gray and the dorsal horn of the spinal cord. We analyzed indetail the distribution of neurotensin-like immunoreactivity in the brain of the Formosan monkey, andcompared these results with those obtained in the brain of the rat, Japanese monkey and human. Somepossible implications regarding differences in location of this peptide are also briefly discussed.
• 中文關鍵字： neurotensin; immunohistochemistry; Formosan monkey
• 英文關鍵字： --