- 作者: 許鵬飛、張智慧、惠新平、張自義、鄭榮樑
- 作者服務機構: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, 730000, P. R. China
- 中文摘要: Compounds 2-arylamino-5-cinchophenyl-1,3,4-oxadiazoline (7) and 3-thio-4-amino-5-cinchophenyl-1,2,4-triazole (3) have been synthesized utilizing cinchophen as the starting material. The compound 3-cinchopheny-s-triazolo[3,4-b]-1,2,3,4-thiatriazole (4) was prepared from compound 3. Condensation of 3 with aromatic acid in the presence of POCl3 gave 10 new 6-aryl-3-cinchopheny-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles (5). Some of the representative compounds were screened for antibacterial activity. The structures of these new compounds have been confirmed by means of elemental analysis, IR, 1H NMR and MS.
- 英文摘要: --
- 中文關鍵字: Cinchophen; Synthesis; Triazoles; Oxadiazoles; Condensed heterocyclic compounds; Biological activity.
- 英文關鍵字: --