• 作者： 謝麗珊; 孫慧芬; 李樞
• 作者服務機構： 私立中原大學化學系
• 中文摘要： 前列腺素E 9-酮基還原?可催化前列腺素E2成為前列腺素F2α，已經從豬腎中分離出來，這個須要NADPH的酵素
  可用光譜測量法來研討，前列腺素E2的KM值得出是180μM，在這個酵素系統中，前列腺素E29-酮基還原?受益母草
  水浸液的影響而加強，因此，益母草可能會影響到前列腺素E2轉換前列腺素F2α的量。這個發現對將益母草在醫學上的
  生理角色提供了一個可能的解釋。5
• 英文摘要： The enzyme system, prostaglandin E 9-ketoreductase, which catalyzes the reduction of prostaglandinE to form prostaglandin F has been partially purified from swine kidney. This NADPH-linked enzyme isstudied spectrophotometrically. The KM of this enzyme for prostaglandin E2 was found to be 180 μM.Studies with the partially purified enzyme indicate that prostaglandin E 9-ketoreductase is affected by aChinese herbal medicine i-mu-ts'ao (leonurus heterophyllus sweet). An increase in the concentration of i-mu-ts'ao aqueous extract may influence the conversion of prostaglandin E2 into prostaglandin F2α. Thisfinding offers a possible explanation for the physiological role of i-mu-ts'ao when it is treated as a medicine.
• 中文關鍵字： --
• 英文關鍵字： --