- 作者: Ching-Nan Ou
- 作者服務機構: Department of Pathology, Texas Children's Hospital and Baylor College of Medicine, Houston, Tex., USA
- 中文摘要: --
- 英文摘要: This report describes a unique cation exchange high-performance liquidchro-matography capable of separating more than 40 frequently encountered human hemoglobins and variants within 12 min. Some of these variants are unresolvable by the conventional electrophoretic methods and would thus lead to an incorrect diagnosis of hemoglobinpathy. The method provides high sensitivity, superior resolution and accurate quantitation of hemoglobin concentrations. It can also be fully automated thus make it an ideal methodology for the diagnosis of hemoglobin disorders in a routine clinical laboratory.
- 中文關鍵字: --
- 英文關鍵字: Hemoglobin variant ; Hemoglobinopathy ; High-performance liquid chromatography ; Cation exchange ; Chromatography