- 作者: 孫宗賢,王志偉
- 作者服務機構: Department of Chemistry, National Sun Yat Sen University, Kaohsiung, Taiwan 804, R.O.C.
- 中文摘要: The (2E,4E)- and (2E,4Z)-1-phenyl-1,6-dioxo-hepta-2,4-diene reacts with aziridine to give aziridine- cyclopentenol 3. This product arises from an intermolecular Michael addition of a nitrogen lone pair to the less reactive enone, followed by an intramolecular aldol reaction of the enol with ketone. Furthermore, the initially formed enol did not undergo nucleophilic attack onto the aziridine ring to form heterocycles. Interestingly, the reaction with secondary amine did not give the cyclopentenol adduct, and this only leads to the isomerization of (2E,4Z)-1-phenyl-1,6-dioxo-hepta-2,4-diene to the more stable (2E,4E)-1-phenyl-1,6-dioxo-hepta-2,4-diene by addition to the more reactive enone.
- 英文摘要: --
- 中文關鍵字: 1,6-Dioxo-2,4-diene; Aziridine; Secondary amine.
- 英文關鍵字: --