• 作者： 陳明彥; 蔡志文; 張茂松; 陳慶真
• 作者服務機構： Institute of Biomedical Engineering Yang-Ming Medical College; Veterans General Hospital; Colleag of General Studies Boston University
• 中文摘要： 此研究的目的，在利用核磁共振影像（MRI）中之磁化向量空間調變（SPAMM）技術來分析心臟每一瞬間心肌運動的狀況，以作為臨床上早期偵測心肌梗塞之應用。 磁化向量空間調變方法是在傳統多重自旋回音（spin echo）波序取像前，加上兩組二項分佈硬波（binomial hard pulse）及磁場梯度（即Gx或Gy）交錯的波序，於是便產生了兩組互相垂直且明暗相間的網狀陣列平行面，而此兩組平行面皆垂直於取像面。在我們研究的資料庫中，包含了模型測試，六位正常人及四位病患。藉著分析左心室網狀陣列中同一格子在心臟不同週期相位下的變形，計算出病患組格子所受的應力及其圓周方向變短（circumferential shortening），心肌增厚（wall thickness）的百分比遠較正常組為小。因此，我們可確信磁化向量空間調變在評估心肌運動上是一能提供傳統造影方法所不能提供訊息的有效工具。 此研究之所有影像數據，取自台中榮總放射線部之Picker 1.0 T磁振造影系統，後續影像處理則使用HP 9000/300系列工作站。
• 英文摘要： This paper reports a new noninvasive method for detecting a regional myocardial infarction. Themethod consists of superimposing a magnetization grid onto different image planes of the human heart. Inthis study the spatial modulation ofmagnetization (SPAMM) in magnetic resonance imaging was modifiedto accommodate the use of a conventional clinical magnet. The percentages of circumferential shortening(PCS) and the percentages of wall thickening (PWT) during a cardiac cycle were estimated by measuring theamount of deformation of each grid from the end of the diastole to the end of the systole. A small database was established on 10 subjects (6 normal volunteers and 4 patients). Patients with regional myocardialinfarction, when monitored by the modified SPAMM investigation, showed smaller values of PCS andPWT in the areas where myocardial infarction was diagnosed by catheterization. The amount in decrementwas directly proportional to the severity of the regional lesions.
• 中文關鍵字： myocardial infraction; spatial modulation of magnetization; percentage of circumferential shortening; percentages of wall thickening; magnetic resonance imaging.
• 英文關鍵字： --