- 作者: Jaewoo Pak, Jung Hun Lee, Kwang Seung Park, Moonhee Park, Lin-Woo Kang and Sang Hee Lee
- 作者服務機構: 1. Stems Medical Clinic, Seoul, Republic of Korea 2. Department of Biological Sciences, Konkuk University, 1 Hwayangdong, Gwangjingu, Seoul 05029, Republic of Korea 3. National Leading Research Laboratory, Department of Biological Sciences, Myongji University, 116 Myongjiro, Yongin, Gyeonggido 17058, Republic of Korea
- 中文摘要:
- 英文摘要:
Autologous adipose stromal vascular fractions (SVFs) containing adipose tissue-derived stem cells (ASCs) are currently being used in clinical settings for various orthopedic applications for human patients. Due to its potential capability of regenerating cartilage, bone, and tendons, autologous adipose SVFs are being tried in treating patients with osteoarthritis (OA), chondromalacia, meniscus tear, osteonecrosis of the femoral head, and tendon injuries. Here, we have reviewed available human clinical studies with regard to patient applications of autologous adipose SVF containing ASCs, specifically assessing effectiveness and safety in the field of orthopedic disorders. All studies reviewed in this article presents potential benefits of autologous adipose SVF in various orthopedic applications without any serious side effects. - 中文關鍵字:
- 英文關鍵字: Mesenchymal stem cell, Stromal vascular fraction, Autologous adipose tissue-derived stem cells, Effectiveness and safety, Orthopedic applications