• 作者： 蔡行瀚; 林欣榮; 施純仁
• 作者服務機構： 國防醫學院外科學科暨三軍總醫院外科部神經外科; 亞東紀念醫院; 馬偕紀念醫院外科部
• 中文摘要： 將大白鼠之頸上交感神經節做節前切斷及節後切除。比較此兩種方法對腦浮腫及中暑影響之差異。腦浮腫實驗模型之製造係將大白鼠腦皮質給予冷及熱之創傷。此時節前切斷動物腦組織含水量較節後切除者有明顯之降低。中暑實驗模型的製造則將大白鼠置於攝氏四十一度的環境溫度中。實驗結果亦發現節前切斷較節後切除能延遲中暑之發作與延長動物之存活期。本實驗認為預先之頸上交感神經節前切斷對大白鼠腦浮腫及中暑之治療有實質之意義。
• 英文摘要： The preventive effect of pre-ganlionic decentralization (Sympathetic trunk resection) or postgang-lionic excision (ganglionectomy) of the superior cervical ganglia on thermal injury induced brain edema orthe development of heat stroke was assessed in rats. Brain edema was induced by cold or heat injury to thecortex in 24 rats. The results showed that decentralization, but not excision, of the superior cervical gangliagreatly inhibited the formation of brain edema which was subsequently induced. When heat stroke wasinduced by exposing 24 rats to an ambient temperature of 41°C, the latency for the onset of the heatstroke and the survival time after the heat stroke were greatly prolonged by the former surgical procedure,but shortened by the later one. The present study demonstrates the potential benefit to brain edema andheat stroke of the pretreatment with decentralization of the superior cervical ganglia.
• 中文關鍵字： Sympathectomy; cerebral edema; sympathetic ganglia
• 英文關鍵字： --