- 作者: 陳志豪 ; 吳獻仁
- 作者服務機構: 交通大學應用化學系
- 中文摘要: Reactions of 4,6-dimethyl-2.beta.-hydroxy-8-oxo-3,5,7- trioxatetracyclo [ 7.2.1.0/sup 4,11/.0/sup 6,10/ ] dodecane(1) with nucleophiles have been studied. Reaction of (1) with alcohols, triethylsilane, allyltrimethylsilane, and methylthiotrimethylsilane in CH/sub 2/Cl/sub 2/ in the presence of TiCl/sub 4/ gave the substitution products in 80-90% yields. The substitution reaction took place chemoselectively on the hemiacetal group of (1). Reaction of (1) with cyanotrimethylsilane in CH/sub 2/Cl/sub 2/ in the presence of TiCl/sub 4/ gave compound 8 and the rearranged product (9). The structure of (9) was proven by X-ray analysis.
- 英文摘要: --
- 中文關鍵字: Chemical Transformation; Substitution Reaction; Chemoselection; X-Ray Analysis
- 英文關鍵字: 化學轉形;取代反應;化學選擇性;X射線分析