• 作者： 孫瑞昇; 曾永輝; 侯勝茂; 韓毅雄; 劉堂桂; 鄭誠功; 曹金耀
• 作者服務機構： 台大醫學院附設醫院骨科; 台大醫學院醫工室
• 中文摘要： 為了探討骨骼肌之特性，我們利用MTS材料試驗機對紐西蘭白兔之腓骨長肌，橡膠及塑膠兩種材料作測試，在麻醉全身之後，先將兔子之腓長肌解剖出來，再用Bionix858 MTS材料測試機將其被動牽引至完全斷裂為止，測試後肌肉及非生命物質之負載-變形曲線（load-deformation curve），分別繪出並加以分析。結果顯示肌肉之負載-變形曲線可以區分為四部分。第一、黏彈部分（viscoelastic）；第二、顯微衰竭部分（microfailure）；第三、巨觀衰竭（macro-failure）；第四、肌肉斷裂及分離。此衰竭機轉的形成主要由於肌肉組織內肌凝蛋白、肌動蛋白之鍵結所造成。經由對肌肉組織顯微衰竭機轉之闡明，我們可以瞭解到正常肌肉組織之功能容量及其極限；而此種極限將可運用運動醫學及復健醫學上被動牽引之肌肉復健，以有效避免不必要之額外傷害。
• 英文摘要： To study the material properties of the skeletal muscle-tendon unit, the peroneus longus muscle ofa rabbit, rubber and plastic materials were tested with on MTS machine. After anesthesia, the peroneuslongus muscle of a rabbit was dissected out and then stretched to failure by an MTS Bionix 858 machine.The load-deformation curves of the muscle and non-biological materials were analyzed and compared. Theresults showed that the load-deformation curve of a muscle-tendon unit can be separated into 4 differentportions: first, the viscoelastic portion, which corresponds to the physiological range of motion; second,the portion of microfailure; third, the portion of macrofailure; and fourth, the portion of rupture andseparation of a muscle-tendon unit. The cause of these behaviors are explained by the presence of actin-myosin cross bridges. Elucidation of the existence of microfailure of skeletal muscle gives a good referencepoint to determine the functional capabilities and limitation of muscular tissue. This will be useful in deter-mining the beneficial effect of stretch programs in sports and rehabilitation and preventing the potentialimpact of tissue injury.
• 中文關鍵字： viscoelasticity; microfailure; macrofailure; skeletal muscles.
• 英文關鍵字： --