- 作者: 張夢揚,林俊佑,孫珮珮
- 作者服務機構: Department of Applied Chemistry, National University of Kaohsiung, Kaohsiung 811, Taiwan, R.O.C.
- 中文摘要: A straightforward synthesis of phenylalanine analogs is described. Cerium ammonium nitrate (CAN) mediated addition of azide to cinnamic ester, followed by reaction with sodium acetate afforded the a-azidocinnamate in moderate yield. Hydrogenation of a-azidocinnamate, followed by BOC, CBZ or Fmoc protection gave phenylalanine analogs. A new approach for synthesizing racemic p-boronophenylalanine analog was also explored.
- 英文摘要: --
- 中文關鍵字: Phenylalanine; Cerium ammonium nitrate; p-Boronophenylalanine; Hydrogenation; Protection.
- 英文關鍵字: --