- 作者: 葉茂榮; 田憲儒
- 作者服務機構: Department of Chemistry, National Cheng Kung University, Tainan, Taiwan 700, R.O.C.
- 中文摘要:
In the presence of pyridine, 3-aryl-4-formylsydnone (II) reacts with hydroxylamine hydrochloride to produce 3-aryl-4-formylsydnone oxime (III). This reaction was performed in ethanol solution with reflux or at room temperature; the latter procedure gave an excellent yield (74-98%) and high purity.
(III) reacts in acetic anhydride at room temperature to give 3-aryl-4-formylsydnone oxime O-acetate (IV).
A convenient method for the synthesis of 3-aryl-4-cyanosydnone (V) is to dehydrate (III) with acetic anhydride at reflux. When (IV) was refluxed with acetic anhydride, (V) was similarly obtained. Another convenient method to prepare (V) from (III), dehydration with thionyl chloride at room temperature, was also investigated. - 英文摘要: --
- 中文關鍵字: 3-(2,4-dimethoxyphenyl) sydnone; 3-(2,4-dimethoxyphenyl)-4-formylsydnone; 3-aryl-4-cyanosydnone; 3-aryl-4-formylsydnone oxime; 3-aryl-4-formylsydnone oxime O-acetate.
- 英文關鍵字: 3-(2,4-dimethoxyphenyl) sydnone; 3-(2,4-dimethoxyphenyl)-4-formylsydnone; 3-aryl-4-cyanosydnone; 3-aryl-4-formylsydnone oxime; 3-aryl-4-formylsydnone oxime O-acetate.