- 作者: --
- 作者服務機構: Department of Chemistry, University of Peshawar, N.W.F.P., Pakistan
- 中文摘要: A simple and rapid spectrophotometric method has been investigated for the determination of furosemide. The method is based upon simple diazotization reaction. The absorbance was measured at 480 nm. The method is optimized for acidity, amount of reagents required and heating time. The range of linearity was 0.4-10 mg mL-1 of furosemide with molar absorptivity of 1.0 ’ 104 l mol-1 cm-1. Standard deviation, co-efficient of variance, limit of detection and limit of quantification were calculated using authentic standard of furosemide and were found to ± 0.0013, 12.7%, 0.16 ppm and 0.52 ppm, respectively. The method was applied to various pharmaceutical preparations containing furosemide. The results of the investigated method for furosemide were compared with available official literature method. The results obtained by the proposed method agree well with the standard established method.
- 英文摘要: --
- 中文關鍵字: Furosemide; Pharmaceutical preparation; Spectrophotometric; Diazotization.
- 英文關鍵字: --