- 作者: Victoria A. Lawson; Jia-Yee Lee; Jennifer C. Doultree; John A. Marshall; Dale A. McPhee
- 作者服務機構: AIDS Cellular Biology Unit, National Centre for HIV Virology Ressearch, Macfarlane Burnet Centre for Medical Research, Fairfield, and Victorian Inferctious Diseases Reference Laboratory, North Melbourne, Australia
- 中文摘要: --
- 英文摘要: Virions produced after HIV-1 infection of HTLV-I trans-formed cells have an expanded tropism that has beenattributed to the presence of HTLV-I glycoproteins in theenvelope. This report now directly identifies these phe-notypically mixed virions by immunogold labelling elec-tron microscopy. Furthermore we estimate there are 2%of these in cell-free supernatant, which represents up to1 × 10 particles/ml from an in vitro infection. HTLV-1envelope labelling was localised to a single region, sug-gesting a defined event in packaging of foreign envelopeproteins into HIV-1 virus particles.
- 中文關鍵字: --
- 英文關鍵字: --