- 作者: --
- 作者服務機構: Department of Chemistry, Faculty of Girls, Ain Shams University, Helipolis post code No. 11757, Cairo, Egypt
- 中文摘要:
Various pyridazin-3(2H)-ones, 3-chloropyridazines and pyridazin-3(2H)-thiones were synthesized and treated with the sulpha drug (knowing by sulphamethoxazole). All the new compounds were evaluated for their antibacterial activity. They showed significant antibacterial activity against Staphylococcus aureus and Bacillus subtilis (Gram + ve) and E. coli, Pseudomonas aeruginosa and Yersinia enterocolitica (Gram - ve) bacteria by agar plate diffusion method.
All proposed structures were confirmed by IR, 1H NMR, Mass spectra and Elemental analysis. - 英文摘要: --
- 中文關鍵字: Pyridazin-3(2H)-one; Antibacterial activity.
- 英文關鍵字: --