- 作者: 劉剛劍; 段英; 石碧珍
- 作者服務機構: Department of Pharmacy, National Defense Medical Center
- 中文摘要: Treatment of aliphatic 1, 2-, 1, 3- or aromatic o-diamine with carbon disulfide provided the corresponding cyclic pseudothioureas (IIB-j). Heating thiourea (IIa) or these compounds with dimethyl or diethyl acetylenedicarboxylate (IIIa, b) in ethanol resulted a nucleophilic addition of the sulfhydryl group to the C≡C bond accompanied with a ring-closure condensation. Thus a series of alkoxycarbo-methylidene derivatives of 2-imino-4-thiazolidinone (IVa), imidazolo-, benzimidazo-and tetrahydropyrimido (2,1-b)-3-thiazolidinones (IVb-k) was produced. An orientating experiment of saponifying the ester function of these compounds has also been carried out.
- 英文摘要: --
- 中文關鍵字: --
- 英文關鍵字: --