- 作者: 盧天惠; 戴伊洛夫; 劉剛劍; 石碧珍; 徐令儀
- 作者服務機構: 國立清華大學物理系; 國防醫學院藥學系
- 中文摘要: 標題的化合物是一種中樞神經系統腫瘤生長細胞新型抑制劑,由本實驗室合成,並以X光繞射定其單晶結構。由乙醇溶液中長出很薄的單晶,屬正交晶系,空間群為Pc21b,元室尺寸是a=6.832(2),b=18.953(4),c=15.744(6)埃,分析結果,權重R因數為0.068。素對稱單位含兩個化合物分子。此雙分子的兩側環相交之二面角少於7度。
- 英文摘要: The title compound, a new inhibitor to the growth of human CNS tumor cells, was synthesized inour laboratories and subjected to X-ray structure determination. Analysis of the extremely thin crystal,grown from the ethanol solution, resulted in the orthorhombic system, space group Pc21b, cell dimensionsa = 6.832 (2), b = 18.953 (4), c = 15.744 (6) and final weighted R factor 0.068. Two molecules of thetitle compound were located in an asymmetric unit. The lateral rings of the two molecules intersectedwith dihedral angles at less than 7°.
- 中文關鍵字: X-ray crystal structure determination; antihypertensive agent; antineoplastic agent.
- 英文關鍵字: --