- 作者: 李水盛 ; 楊行健
- 作者服務機構: 台灣大學藥學系
- 中文摘要: By combination of centrifugal partition chromatography(CPC) and common separation methods, twelve known bases were isolated and characterized from the first chemical investigation of Neolitsea konishii (H.) K. & S. They belong to isoquinoline alkaloids of four types: eight aporphines, nornuciferine, N-methyllaurotetanine, laurolitsine (3), boldine, laurotetanine, isoboldine (6), actinodaphine and corytuberine; two proaporphines, stepharine and glaziovine; one benzylisoquinoline, reticuline (11); and one morphinan, pallidine. Among these, compounds 3, 6 and 11 are abundant and will be modified for pharmacological tests. The content of various alkaloids in the plant is useful as a basis for chemotaxonomy.
- 英文摘要: --
- 中文關鍵字: Neolitsea Konishii; Cpc; Isoquinoline Alkaloid; Aporhines; C-13 Nmr; N-Methylation Shift; Benzylisoquinoline; Proaporphine; Morphinan; Chemotaxonom
- 英文關鍵字: 離心分離層析;異生物鹼;阿朴啡;碳十三核磁共振;N-甲基化轉移;芐基異;原阿朴啡;嗎啡;化學分類學