- 作者: --
- 作者服務機構: Department of Chemistry, Faculty of Science, Al-Azhar University at Assiut, Assiut 71524, Egypt
- 中文摘要: A new series of hydroquinolines 6a-d, 10, 12, 15, 17b, 20 and pyrimidoquinolines 7, 8, 9a, 11, 14 and 16 were synthesized starting from 2-amino-4-(3-bromo-phenyl)-7,7-dimethyl-1-naphthalen-1-yl-5-oxo-1,4,5,6,7,8-hexahydro-quinoline-3-carbonitrile 6b. The structures of the synthesized compounds were elucidated by elemental analyses and spectral data. Compounds 6a, 10, 11 and 18 exhibited a remarkable antifungal activity compared with fungicide Mycostatine. Radiosterilization of the biologically active compounds 6a, 10 and 11 in the dry state may prove to be applicable [retaining their structures unchanged up to (40 kGy)].
- 英文摘要: --
- 中文關鍵字: Hydroquinoline; Pyrimido[4,5-b]quinoline and radiation stability.
- 英文關鍵字: --