- 作者: 范秉真; 徐郁坡; 趙大衛; 劉和榮; 李金木; 鄭?鶯; 王錦惠; 李世雄
- 作者服務機構: 國立陽明醫學院寄生蟲學科及榮民總醫院醫學研究部寄生蟲研究室
- 中文摘要: For evaluation of control of Bancroftianfilariasis by common salt medicated with diethyl-carbamazine (DEC) on Kinmen (Quemoy) Islandsthe pre-control microfilarial carriers and inhabi-tants were re-examined by millipore membranefiltration technique (MMFT) and physical exami-nation from June 1,1978 to May 31,1979. Theobtained results are summarized as follows: 1. Five years post-control on Little Kin-men (Leihyu District) the venous blood sampleswere taken from 213 pre-control microfilarialcarriers in 15 villages and 77 inhabitants in PutouTsuen, then examined by MMFT, no microfilarialcarrier was found. 2. Two years post-control on Kinmen Proper(Ta-Kinmen) the venous blood samples of 1,538pre-control microfilarial carriers in 77 villages,216 inhabitants in 2 villages and 22 old personsin Kincheng Nursing House were collected andexamined, the negative finding was found except3 pre-control microfilarial carriers still remainedin positive. 3. For blocking the possible source of fil-arial infection 79 overseas Kinmenese were ex-amined during visiting their native towns onKinmen Islands, all of them were shown negative. 4. Physical examination on 1,335 pre-control microfilarial carriers was performed. Inthe examination,343 carriers were demonstratedas clinical cases before control, the clinical mani-festations completely disappeared from 124 pre-control clinical cases, giving the clinical reduc-tion rate of 36.2%. 5. Analysis of the obtained physical datafrom a total of 365 pre- and post-control clinicalcases was performed, it showed that the clinicalmanifestations disappeared in 40%, improved16.7%, and there was no change in 32.2%. Butnewly occurred in 6%, and 5% increased inseverity. Therefore, the DEC medicated salt isalso effective to the acute and subacute stagesof clinical manifestations, bat it seems probablyno effect to the chronic cases of elephantiasis.On the other hand a reverse proportion of theclincial reduction rate to the number of clinicalmanifestations was also demonstrated.
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