- 作者: Ching-Ying Huang, Chun-Lin Liu, Chien-Yu Ting, Yueh-Ting Chiu, Yu-Che Cheng, Martin W. Nicholson and Patrick C. H. Hsieh
- 作者服務機構: 1. Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan 2. Graduate Institute of Medical Genomics and Proteomics and Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan 3. Cardiovascular Surgery Division, Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan
- 中文摘要:
- 英文摘要:
The introduction of induced pluripotent stem cells (iPSCs) has opened up the potential for personalized cell therapies and ushered in new opportunities for regenerative medicine, disease modeling, iPSC-based drug discovery and toxicity assessment. Over the past 10 years, several initiatives have been established that aim to collect and generate a large amount of human iPSCs for scientific research purposes. In this review, we compare the construction and operation strategy of some iPSC banks as well as their ongoing development. We also introduce the technical challenges and offer future perspectives pertaining to the establishment and management of iPSC banks. - 中文關鍵字:
- 英文關鍵字: Induced pluripotent stem cell (iPSC), Cell bank, Personalized medicine