- 作者: Chun-Ching Lin a, Hua-Yew Cheng b, Chien-Min Yang a, Ta-Chen Lin c
- 作者服務機構: a Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University , Kaohsiung, b Graduate Institute of Pharmaceutical Science , College of Pharmacy , Kaohsiung Medical University , Kaohsiung , c Department of Pharmacy , Ta-Jen Institute of Technology , Ping-Tung , Taiwan , ROC
- 中文摘要: --
- 英文摘要: The antioxidant and antiviral activities of Euphorbia thy-mifolia L. (Euphorbiaceae) were investigated in thisstudy. The results showed that all of the fractions (MeOH,CHC13, EtOAc, n-butanol and water) and pure com-pounds (3-O-galloyl-4,6-(S)-HHDP-D-glucose, rugosin Band 1,3,4,6-tetra-O-galloyl-K-β-D-glucose)tested pos-sessed antioxidant activities, with the exception of theorganic aqueous fraction in the anti-lipid and anti-super-oxide formation assays. The range of IC5o of anti-lipid for-mation, anti-superoxide formation and free radical scav-enging assays for all fractions and pure compoundswere 2.81-7.63, 0.03-2.18 and 0.013-2.878 mg/ml, re-spectively. Electron spin resonance studies showed thatwater extract and pure compounds of E. thymifolia ex-hibited superoxide radical and hydroxyl radical scaveng-ing activities. Besides antioxidant activities, 3-O-galloyl-4,6-(S)-HHDP-D-glucose and EtOAc fraction also showedanti-HSV-2 activity. Thus, E. thymifolia was concluded topossess antioxidant and anti-HSV-2 activities.
- 中文關鍵字: --
- 英文關鍵字: Euphorbia thymifolia, Antioxidant activity, Anti-HSV-2 activity