- 作者: 袁谷
- 作者服務機構: Department of Chemical Biology, The Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Ministry of Education, College of Chemistry, Peking University, Beijing 100871, P. R. China
- 中文摘要: A simple procedure for the systematical synthesis of eight distamycin analogues containing N-methylpyrrole (Py) and N-methylimidazole (Im) has been developed by a chloroform reaction and DCC coupling reaction without amino protection and deprotection, and the interaction of the analogues with Herring Sperm DNA was investigated by fluorescence spectroscopy.
- 英文摘要: --
- 中文關鍵字: Distamycin; Synthesis; Chloroform reaction; Fluorescence; DNA
- 英文關鍵字: Distamycin; Synthesis; Chloroform reaction; Fluorescence; DNA