- 作者: 楊雅萍 ; 丁美芳 ; 王禹文 等
- 作者服務機構: 中興大學化學系
- 中文摘要: Selective ring opening of the cyclopropyl moiety of binor-S was accomplished by several methods including acidic hydrolysis, bromination, and hydrobromination. The crystal structure of dibromide adduct (3) was solved by X-ray diffraction analysis. Debrominations of (3) yielded either(1) or (4a), whereas dehydrobormination yielded a 3- substituted monobromide (6a). The mechanism of conversion of (3) to (6a) is depicted as involving intermediate (7); the existence of (7) is supported by the isolation of olefin. Oxidation of alcohol produced ketone which was either oxidized to lactone or transformed to a methylene derivative (11b). Hydroboration of (11b) followed by quenching with hydrogen peroxide produced a hydroxymethyl derivative.
- 英文摘要: --
- 中文關鍵字: Binor-S; Bromination; Dehydrobromination; Cyclopropyl Ring; Ring Opening
- 英文關鍵字: 溴化反應;去氫化溴反應;環丙烷環;開環反應