- 作者: 許志宏 ; 宋秉鈞
- 作者服務機構: 中山大學海洋資源系
- 中文摘要: A highly cytotoxic hydroperoxysterol 24-hydroperoxy-24-vinylcholesterol (1) and fucosterol were isolated from the brown alga Turbinaria conoides, Compound (1) was transformed into 29-hydroperoxystigmasta-5,24(28)-dien-3.beta.-ol in chloroform solution at -5 to 0.degree.C in quantitative yield. The latter compound has been shown to exhibit much stronger cytotoxicity toward cultured spleen lymphocytes stimulated by mitogen concanavalin A than toward normal spleen lymphocytes.
- 英文摘要: --
- 中文關鍵字: Brown Algae; Turbinaria Conoides; Hydroperoxy Steroid; Selective Cytotoxicity; Mitogen; Natural Product
- 英文關鍵字: 褐藻;類固醇;選擇性細胞毒性;分裂素(分裂原);天然物