- 作者: Yan Zhang, Ren-Zhong Qiao, Peng-Fei Xu*, Zi-Yi Zhang*, Qin Wang, Li-Min Mao and Kai-Bei Yu
- 作者服務機構: College of Chemistry and Chemical Engineering, National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, 730000, P. R. China
- 中文摘要: Eighteen novel 2-(1-aryl-5-methyl-1,2,3-triazol-4-yl)-1,3,4-oxadiazole derivatives and two acylhydrazone intermediate compounds were synthesized by various pathways starting from 1-aryl-5-methyl-1,2,3-triazol-4-formhydrazide (1). All products were identified by spectroscopic analysis, and 2-(1-aryl-5-methyl-1,2,3-triazol-4-yl)-5-benzalthio-1,3,4-oxadiazole was further validated by X-ray crystallography. Results from primary antibacterial activity tests indicated that most of the compounds were effective against E. coli, P. aeruginosa, B. subtilis and S. Aureus.
- 英文摘要: --
- 中文關鍵字: 1,2,3-Triazole; 1,3,4-Oxadiazole; X-ray crystallography; Antibacterial test.
- 英文關鍵字: 1,2,3-Triazole; 1,3,4-Oxadiazole; X-ray crystallography; Antibacterial test.