- 作者: Wendy Maury
- 作者服務機構: Department of Microbiology, University of South Dakota School of Medicine, Vermillion, S. Dak., USA
- 中文摘要: --
- 英文摘要: Equine infectious anemia virus (EIAV) is an ungulate lentivirus that is related to human immunodeficiency virus (HIV). Much of the understanding of len-tiviral gene regulation comes from studies using HIV. HIV studies have provided insights into molecular regulation of EIAV expression; however, much of the regulation of EIAV expression stands in stark contrast to that of HIV. This review provides an overview of the current state of knowledge of EIAV regulation by comparing and contrasting EIAV gene regulation to HIV. The role of EIAV gene regulation is discussed in relation to EIAV pathogenesis.
- 中文關鍵字: --
- 英文關鍵字: Lentivirus; Retrovirus; Gene expression; Equine infectious anemia virus; Tat; Rev; Splicing ; Cytokine; Transcription factor ; Nucleotide variation ; Viral pathogenesis