- 作者: 陸大榮 ; 劉秀文
- 作者服務機構: 中興大學化學系
- 中文摘要: The reduction of prochiral ketones using chiral reducing reagents, prepared from lithium aluminum hydride and (-)-(1R,2S,3S,5R)-10-anilinopinanediol (5) and (-)-(1R,2S,3S,5R)-10-N-methylanilinopinanediol (6), affords chiral secondary alcohols in useful chemical yields (70 to 93%) but in low optical purity (8 to 33% ee). Modifiers (5) and (6) are synthesized from (1R)-(-)-.beta.-pinene in three steps.
- 英文摘要: --
- 中文關鍵字: Asymmetric Reduction; Lithium Aluminum Hydride; Pinene; Aminodiol
- 英文關鍵字: 不對稱還原;氫鋁酸鋰;苹烯;胺基二醇