- 作者: 洪永 ; 孫珮珮 ; 盧惠玲 等
- 作者服務機構: 中央研究院化學研究所
- 中文摘要: Several (E)- and (Z)-.omega.-formyl-5-oxa-2- substituted-.alpha.,.beta.-unsaturated esters were prepared in high yields. They were subjected to cyclization of their intramolecular ketyl radicals induced by either samarium(II) iodide or tributyltin hydride. These two reagents gave distinct stereoselectivities. More bicyclic lactone than monocyclic hydroxy-ester was formed when tributyltin hydride was used, but the opposite stereoselectivity was obtained when samarium(II) iodide was used. The effect of double-bond configuration, heteroatom and substituent on stereoselectivity is described.
- 英文摘要: --
- 中文關鍵字: Ketyl Radical; Radical Cyclization; Samarium Iodide; Tributyltin Hydride; Ozonolysis; Bicyclic Lactone; Tetrahydrofurans
- 英文關鍵字: 酮自由基;自由基環化;碘化釤;氫三丁基錫;臭氧解;雙環內酯;四氫喃