- 作者: 范秉真; 趙大衛; 劉和榮; 李金木; 鄭峰鶯; 王錦惠; 李世雄
- 作者服務機構: 國立陽明醫學院寄生蟲學科及榮民總醫院醫學研究部寄生蟲學研究室
- 中文摘要:
在目前研究中,腸道寄生蟲之檢查應用福爾馬林-乙醚濃縮法,蟯蟲之檢查採用玻璃膠紙肛
圍擦拭法。治療陽道寄生蟲之藥物,採用廣效、安全及易服之康保寧及邁苯達早,其結果簡述如
下:
1. 宜蘭地區中學生腸道寄生蟲之傳染率,以蟯蟲(42%)最高,鞭蟲(33%)次之,蛔蟲
(15%)較低,?蟲(4%)最低。在性別上,女生蟯蟲之傳染率(47%)顯較男生為(37%)高。惟
女生鞭蟲、蛔蟲及?蟲之傳染率(33, 14 及 3.4%)與男生者(33, 15 及 4.5%),則無顯著差異。
2. 治療蟯蟲時,邁苯達早之最低有效劑量為 10 mg,而康寶寧之最低有效劑量較 100 mg
最高,需待進一步之證明。a - 英文摘要: In the present study, both formol-ether con-centration technique (FECT) and scotch tapeperianal swab (STPS) were used for diagnosis ofthe common intestinal nematode parasites. Atthe same time, two new broad-spectrum an-thelmintics of mebendazole (vermox) and pyr-antel pamoate (combantrin) were also used inthe treatment of the above worms and evaluationof their efficacy as well as determination of theminimum effective dosage. The last point ismore important in use for the national controlprogram on the common intestinal nematodeparasites among school children on Taiwan inthe near future. The results obtained are summarized asfollows: 1. Infection rate of Enterobius vermicularis(42%) is the highest; Trichuris trichiura (33%),the next; Ascaris lumbricoides (15%), the third;and hookworm (4%), the lowest. 2. Infection rate of Enterobius Ascaris,Trichuris and hookworm in the tape-water sup-ported area of Yuan-Shan and Chiao-Chi (43%,14%, 36%, and 4.6% respectively) and that innon-tape-water supported area of Chuang-Weiand Tou-Cheng (39%, 15%, 29%, and 3% re-spectively) was no more difference. 3. The minimum effective dosage of meb-endazole in the treatment of enterobiasis, ascar-iasis and trichuriasis was 10, 75 and 300 mgrespectively. The minimum effective dosage ofcombantrin against ascariasis was 400 mg. Butthere was no more effect against trichuriasis,nor could it be determined if used to fight againstenterobiasis. 4. 7,903 worms were collected from 105cases after treatment with combantrin (100 mg)following purgative of mag. sulphate (25 gm),the average number of 1.6 Trichuris, 3.9 Ascaris,3.5 hookoworms and 79.6 Enterobius was obtainedper case. All the species of worms were ap-parently higher in the male worms than in thefemales except Ascaris. 5. 7,722 Enterobius were collected from 97cases, 6,105 (77.2%) were the males and 1,798(22.8%) females. A highest number of 4,864worms were obtained from a heavy infectedcase. 6. Of 91 hookworms, 20 (22%) were An-cylostoma duodenale and 71 (78%), Necator amer-icanus. It is identified that the higher intensityof N. americanus than that of A. duodenale wasfound in Ilan county.
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