- 作者: Mei-Hsiu Shih, Mei-Jin Lee and Mou-Yung Yeh*
- 作者服務機構: Department of Chemistry, National Cheng Kung University, Tainan, Taiwan 701, R.O.C.
- 中文摘要: 3-Arylsydnone-4-carbohydroximic acid chlorides (1) could react with sodium azide to produce the corresponding 3-arylsydnone-4-carbazidoximes (2), but not 1-hydroxytetrazoles 3. Treatment of 3-arylsydnone-4-carbazidoximes (2) with acid chlorides such as acetyl chloride (4a), propionyl chloride (4b) and benzoyl chloride (4c) in the presence of excess triethylamine generated the derivatives of the azidoximes 5. To obtain the desired tetrazoles, the azidoximes 2 should first cyclize directly with acetyl chloride (4a) or propionyl chloride (4b) to afford the acetyl or propionyl derivatives 6. The cyclized tetrazole derivatives 6 underwent deacylation upon heating in ethanol to give 1-hydroxy-5-(3-arylsydnon-4-yl)tetrazoles (3).
- 英文摘要: --
- 中文關鍵字: Sydnones; Nitrile oxides; Carbohydroximic acid chlorides; Azidoximes; Tetrazoles; 3-Arylsydnone-4-carbazidoximies; 1-Acyloxy-5-(3-arylsydnon-4-yl)trazoles; 1-Hydroxy-5-(3-arylsydnon-4-yl)tetrazoles.
- 英文關鍵字: Sydnones; Nitrile oxides; Carbohydroximic acid chlorides; Azidoximes; Tetrazoles; 3-Arylsydnone-4-carbazidoximies; 1-Acyloxy-5-(3-arylsydnon-4-yl)trazoles; 1-Hydroxy-5-(3-arylsydnon-4-yl)tetrazoles.