• 作者： 艾穆拉; 黃陽濱; 席曉蓉; 吳向東
• 作者服務機構： 巴基斯坦拉瓦爾品弟醫科大學生理教研室; 上海醫科大學基礎醫學院
• 中文摘要： 　　背景：目前認為孕激素和雌激素（單獨或聯合）用葯可以影響到眼內壓（IOP），雖然有一些文獻持否定態度。隨月經周期而變化的激素與IOP之問的關係目前尚不明瞭。除去了可干擾IOP的影響因素後，本實驗試圖瞭解生理性隨月經周期而變化的激素是否引起IOP的改變。　　方法：20個已婚同一年齡組且不用避孕葯的婦女在一個月經周期中，每日用Goldmann壓平眼壓計檢測IOP，並測定激素血液度，包括：黃體生成素(LH)、卵泡刺激素(FSH)、雌酮 (E1)、雌二醇(E2)、孕激素和睪峒。　　結果：20個對象的IOP值隨月經周期不同的時問而變化，然而未發現不同時期各激素水平與IOP間的確切關係。　　結論：隨月經周期發生的激素改變對IOP無明確的影響。
• 英文摘要： Background: Despite some findings to the contrary, it would appear that pharmacological doses ofprogesterone and estrogen (alone or in combination) can influence intraocular pressure (IOP). The relation-ship between hormonal changes associated with the menstrual cycle and intraocular pressure is not clearlyunderstood. After elimination of those factors that can affect IOP, the present study investigated whetherphysiological hormonal changes associated with the menstrual cycle have a correlation with intraocular pres-sure. Methods: Intraocular pressure and the concentrations of circulating hormones, namely, theluteinizing hormone（LH), follicle-stimulating hormone (FSH), estrone (E1), estradiol (E2), progesterone,and testosterone, of twenty married women of the same age groups were recorded daily throughout a men-strual cycle. None was taking any contraceptives in any form. The intraocular pressure was measured usinga Goldmann applanation tonometer. Results: The intraocular pressure values fluctuated in each of the twenty subjects at various times ofthe cycle; however, they were not definitely correlated with the different phases of the cycle. This studyfailed to find any correlation between IOP and progesterone or estradiol levels.
• 中文關鍵字： menstrual cycle; ocular tension; sex hormone; tonometry.
• 英文關鍵字： --